Primary Pulmonary Hypertension in a Child | Zendy

B. N. SATYANARAYANA RAO | Zendy; James H. Moller | Zendy; Jesse E. Edwards | Zendy

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Primary Pulmonary Hypertension in a Child

Author(s) -

B. N. SATYANARAYANA RAO,

James H. Moller,

Jesse E. Edwards

Publication year - 1969

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.40.4.583

Subject(s) - medicine , tolazoline , pulmonary hypertension , ventricle , vascular resistance , cardiology , right ventricular hypertrophy , blood pressure , pulmonary arterial pressure , muscle hypertrophy , anesthesia

Clinical, pharmacologic, and pathologic findings presented are those in a 12-year-old boy with primary pulmonary hypertension associated with medial hypertrophy of the pulmonary muscular arteries and arterioles.Intrapulmonary arterial administration of acetylcholine, tolazoline (Priscoline), or isoproterenol resulted in a fall in pulmonary vascular resistance and pressure.Perforation of the right ventricle by an indwelling catheter terminated studies on the results of long-term intrapulmonary arterial administration of drugs shown to be effective.

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