The Distribution of Body Fluids In Congestive Heart Failure
Author(s) -
J. R. Elkinton,
Russell D. Squires
Publication year - 1951
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.4.5.679
Subject(s) - heart failure , medicine , circulatory system , body fluid , cardiology , pathogenesis , circulatory collapse
The pathogenesis of congestive heart failure is discussed. Experimental evidence is cited to support the thesis that abnormalities in the distribution of body fluids may affect circulatory and renal function, and hence may be a cause as well as an effect in the complex sequence of events leading to the congestive state. Emphasis is placed upon alterations in cellular metabolism which may lead to such disturbances in body fluids and so through various mechanisms, cellular, humoral, and circulatory, may modify the volume regulation of the body.
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