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The Determination of Cardiac Output by a Continuous Recording System Utilizing Iodinated (I 131 ) Human Serum Albumin
Author(s) -
William J. MacIntyre,
W. H. Pritchard,
RICHARD W. ECKSTEIN,
Hymer L. Friedell
Publication year - 1951
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.4.4.552
Subject(s) - medicine , dilution , cardiac output , calibration , indicator dilution , human serum albumin , calibration curve , biomedical engineering , albumin , blood flow , nuclear medicine , chromatography , hemodynamics , thermodynamics , chemistry , mathematics , statistics , physics , detection limit
A method is outlined for the determination of cardiac output by the injection of iodinated (I131) human serum albumin and continuous recording of the dilution curve. The calibration of the flow system by means of the final dilution and blood volume is discussed along with the possible application to an external measuring method. The results of eight dilution curves obtained from dogs are presented and the calculated cardiac outputs compared with the values measured by the rotameter method.

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