Fiberoptic-Dye Dilution Method for Measurement of Cardiac Output
Author(s) -
Henry R. Wagner,
Walter J. Gamble,
William H. Albers,
Paul G. Hugenholtz
Publication year - 1968
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.37.5.694
Subject(s) - biplane , medicine , angiocardiography , cardiac output , ventricle , stroke (engine) , stroke volume , standard deviation , cardiac catheterization , mean difference , nuclear medicine , heart catheterization , cardiology , confidence interval , mathematics , heart rate , hemodynamics , statistics , blood pressure , mechanical engineering , engineering , aerospace engineering
A new method for the measurement of cardiac output has been tested in 69 patients undergoing catheterization of the right and left sides of the heart. It is based on the recently described fiberoptic hemoreflection method. In order to verify the validity of these measurements, correlations with stroke indices determined by the Fick principle and by biplane angiocardiography were also carried out. Details of the biplane angiocardiographic technique and of the fiberoptic calibration methods are given.Comparisons were carried out in 37 instances between the results after injections in the pulmonary artery (mean stroke index, 40.8 ml/m2) and in the left ventricle (mean, 42.9 ml/m2). Good agreement was found, r=0.930, with a mean difference of 2.1 ml/m2.Stroke indices by fiberoptics (FO) were first compared with those obtained by the standard Fick method. In 100 determinations the mean stroke index by FO was 45.7 ml/m2, and Fick 49.0 ml/m2 (r=0.859; confidence limits, 0.77
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