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Origin of Both Great Vessels from the Right Ventricle Associated with the Trisomy-18 Syndrome
Author(s) -
Terry R. Rogers,
Jack W. C. Hagstrom,
Mary Allen Engle
Publication year - 1965
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.32.5.802
Subject(s) - trisomy , medicine , ventricle , down syndrome , cardiology , genetics , biology , psychiatry
Origin of both great vessels from the right ventricle in association with a ventricular septal defect was found in seven of nine autopsied patients with the clinical features of the trisomy-18 syndrome. In four of these patients trisomy-18 was confirmed by chromosomal analyses. This experience indicates that origin of both great vessels from the right ventricle may in fact be an additional component of the trisomy-18 syndrome. Human Genetics, for chromosomal analyses and for consultation.

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