Late Cardiac Complications of Chronic, Severe, Refractory Anemia with Hemochromatosis | Zendy

Mary Allen Engle | Zendy; Marion E. Erlandson | Zendy; Carl H. Smith | Zendy

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Late Cardiac Complications of Chronic, Severe, Refractory Anemia with Hemochromatosis

Author(s) -

Mary Allen Engle,

Marion E. Erlandson,

Carl H. Smith

Publication year - 1964

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.30.5.698

Subject(s) - medicine , hemochromatosis , complication , heart failure , anemia , pericarditis , sepsis , cardiology , surgery

Four fifths of 49 patients with chronic, severe anemia from birth have manifested, usually during the second decade, signs of hemochromatosis with cardiac involvement. Nineteen patients had 33 attacks of pericarditis. Congestive cardiac failure with arrhythmias developed in 26 patients, and all but one died with this complication. Four others died of sepsis before heart failure was evidenced. Postmortem examination showed hemochromatosis with severe myocardial involvement.

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