Effect of Exercise on Cardiac Performance in Human Subjects with Coronary Artery Disease | Zendy

Joseph V. Messer | Zendy; Herbert J. Levine | Zendy; Richard J. Wagman | Zendy; Richard Gorlin | Zendy

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Effect of Exercise on Cardiac Performance in Human Subjects with Coronary Artery Disease

Author(s) -

Joseph V. Messer,

Herbert J. Levine,

Richard J. Wagman,

Richard Gorlin

Publication year - 1963

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.28.3.404

Subject(s) - medicine , cardiology , coronary artery disease , heart failure , cardiac function curve , oxygenation , artery

Cardiac performance and oxygenation have been studied in resting and exercising subjects with coronary artery disease. Disturbances exist in myocardial function and energetics, characterized by preservation of pressure development, but with impaired systolic ejection and failure to increase mechanical efficiency during exercise. Resultant elevation of myocardial oxygen need by impaired performance undoubtedly aggravates coronary reserve inadequacy during exercise.

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