Ultrastructure and Transport Across Epithelial Membranes
Author(s) -
C. Adrian M. Hogben
Publication year - 1962
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.26.5.1179
Subject(s) - bone canaliculus , endoplasmic reticulum , ultrastructure , microbiology and biotechnology , epithelium , intracellular , biophysics , golgi apparatus , extracellular , ion transporter , membrane , biology , medicine , anatomy , pathology , biochemistry
For epithelia, all too frequently this or that ultrastructure is spoken of as “absorptive” or “(secretory.” Correlation between structure and function must relate to phenomena, such as the apparent active transport of weak electrolytes or water, that are unique for the epithelium. The macroscopic tubule of the gastric mucosa cannot sequester the active transport of hydrochloric acid from the solution bathing the mucosa. In the absence of both intracellular canaliculi and a microvillous border from the amphibian parietal cell, by exclusion, the endoplasmic reticulum or the plasma membrane proper must be considered as possible structures responsible for the sequestration.
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