Open AccessThe Excitable System in the Cell Surface
Author(s) -
Julian M. Tobias,
D. Agin,
Raymond Pawlowski
Publication year - 1962
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.26.5.1145
Subject(s) - phospholipid , biophysics , membrane , cell membrane , medicine , component (thermodynamics) , microbiology and biotechnology , model system , cell , lipid bilayer , biochemistry , biological system , biology , physics , thermodynamics
A membrane model, composed of phospholipid and cholesterol, is described. The electrical resistance and hydration of this model can be controlled by manipulation of ambient ions and by current in ways strongly reminiscent of the behavior of living cells. The behavior of the model may resemble that of the membrane component of the cell. In addition, an interdependent, lipid-protein molecular structure may exist at the cell surface.
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