Clinical Diagnosis of Cardiac Involvement in Systemic Lupus Erythematosus | Zendy

Thomas Q. Kong | Zendy; Robert E. Kellum | Zendy; John R. Haserick | Zendy

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Clinical Diagnosis of Cardiac Involvement in Systemic Lupus Erythematosus

Author(s) -

Thomas Q. Kong,

Robert E. Kellum,

John R. Haserick

Publication year - 1962

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.26.1.7

Subject(s) - medicine , autopsy , cardiology , lupus erythematosus , systemic lupus erythematosus , dermatology , systemic disease , immunopathology , immunology , disease , antibody

A review was made of the case histories and autopsy reports of 30 patients with systemic lupus erythematosus who had clinical cardiovascular involvement. The presence of an enlarged heart or of gallop rhythmstrongly suggests myocardial involvement, but the electrocardiogram is not specific. Signs and symptoms referable to the heart are unusual as a first manifestation of systemic lupus erythematosus, and in patients receiving suppressive chemotherapy they do not further worsen the prognosis. Systolic murmurs cannot be interpreted as conclusive evidence of Libman-Sacks valvulitis.

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