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Myocardial Infarction and Atrial Arrhythmias
Author(s) -
Thomas N. James
Publication year - 1961
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.24.4.761
Subject(s) - medicine , cardiology , myocardial infarction , infarction , chronotropic , occlusion , sinus (botany) , coronary arteries , artery , heart rate , blood pressure , botany , biology , genus
In each of 11 necropsied patients with myocardial infarction and atrial arrhythmias, a coronary occlusion was found proximal to the origin of the sinus node artery and there was infarction of the sinus node. The multiple factors influencing the onset of atrial arrhythmias during acute myocardial infarction are discussed. Infarction of the sinus node is only one of these factors. Other important ones are ischemia of the AV node, vagal and vagomimetic reflexes, atrial distention, and circulating chronotropic substances. By combination of a knowledge of the anatomy and pathology of the human coronary arteries with the observation of atrial arrhythmias during acute myocardial infarction, an accurate diagnosis of the point of coronary occlusion can often be made.

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