An Appraisal of the Double Indicator-Dilution Method for the Estimation of Mitral Regurgitation in Human Subjects | Zendy

William S. Wilson | Zendy; Ralph L. Brandt | Zendy; Richard D. Judge | Zendy; Joe D. Morris | Zendy; Mary Clifford | Zendy

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An Appraisal of the Double Indicator-Dilution Method for the Estimation of Mitral Regurgitation in Human Subjects

Author(s) -

William S. Wilson,

Ralph L. Brandt,

Richard D. Judge,

Joe D. Morris,

Mary Clifford

Publication year - 1961

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.23.1.64

Subject(s) - medicine , mitral regurgitation , cardiology , pulmonary artery , autopsy , regurgitation (circulation) , cardiac catheterization , mitral valve , femoral artery , surgery

The amount of mitral regurgitation was estimated in 50 patients by an indicator-dilution technic and by the usual clinical, catheterization, operative, and autopsy criteria. There was a good correlation between the two estimates. Patients with significant mitral regurgitation (grade 2 or grade 3) had, with one exception, QR/QF ratios above 0.41. There were at least two instances where the calculated QR/QF was almost certainly falsely high. It seems likely that these discrepancies are related to the presence of an unusually large volume between the pulmonary artery and the femoral artery.

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