The Effect of Smoking upon Blood Flow in the Sympathectomized Limb | Zendy

Samuel I. Rapaport | Zendy; Hugh A. Frank | Zendy; Theodore B. Massell | Zendy

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The Effect of Smoking upon Blood Flow in the Sympathectomized Limb

Author(s) -

Samuel I. Rapaport,

Hugh A. Frank,

Theodore B. Massell

Publication year - 1950

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.2.6.850

Subject(s) - medicine , sympathectomy , vasospasm , vasoconstriction , constriction , vasomotor , arteriosclerosis obliterans , cardiology , curare , blood flow , anesthesia , reflex , subarachnoid hemorrhage

The effect of smoking upon the blood flow of a sympathectomized limb was examined in 19 patients. Sympathectomy was found to abolish the peripheral vasoconstriction produced by smoking. The constriction, therefore, is mediated by sympathetic vasomotor fibers and not by humoral agents such as adrenaline or posterior pituitary hormone. There is no difference in the response of patients sympathectomized for thromboangiitis obliterans, arteriosclerosis or severe vasospasm. The relation between the vasoconstrictor effect of smoking and the action of tobacco in thromboangiitis obliterans is discussed.

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