Atypical Secondary or Symptomatic Thrombocytopenic Purpura Developing with the Use of Quinidine Sulfate | Zendy

Donald C. Collins | Zendy

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Atypical Secondary or Symptomatic Thrombocytopenic Purpura Developing with the Use of Quinidine Sulfate

Author(s) -

Donald C. Collins

Publication year - 1950

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.2.3.438

Subject(s) - medicine , quinidine , thrombocytopenic purpura , quinine , purpura (gastropod) , thrombotic thrombocytopenic purpura , dermatology , pediatrics , malaria , immunology , pharmacology , platelet , biology , ecology

Quinidine sulfate, which has a very similar chemical structural formula to that of quinine bisulfate, may on a rare occasion be the etiologic causative agent of an atypical secondary or symptomatic thrombocytopenic purpura of serious degree. Fortunately, the withdrawal of the drug results in a rapid return to normal of the hematologic picture. A case report of such an occurrence is presented. Three additional case reports have been collected from the literature since 1941.

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