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Effect of Khellin on Coronary Artery Insufficiency as Evaluated by Electrocardiographic Tests
Author(s) -
Maurice M. Best,
Walter S. Coe
Publication year - 1950
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.2.3.344
Subject(s) - medicine , ergonovine , cardiology , angina , electrocardiography , st segment , artery , myocardial infarction
The effectiveness of khellin in 9 patients with angina pectoris was evaluated electrocardiographically by means of the exercise tolerance, anoxemia and ergonovine tests. Normalization occurred in the majority of the previously abnormal tests following khellin therapy. A beneficial effect was noted on symptoms accompanied by a reduction in nitroglycerin requirement. Mild toxicity, as a result of khellin therapy, was observed in 3 cases.

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