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Osmole and Water Excretion in Mercurial Diuresis in Congestive Heart Failure
Author(s) -
Norton Spritz,
George W. Frimpter,
WARREN S. BRAVEMAN,
Albert L. Rubin
Publication year - 1959
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.19.4.600
Subject(s) - diuresis , medicine , heart failure , excretion , edema , diuretic , endocrinology , cardiology , renal function
The relationhip between water and total solute excretion following mercurial administration has been previously studied in normal human subjects during superimposed water and solute diureses. It is the purpose of the study to determine the solute/water relationships in the mercurial diuresis produced in water-deprived patients with edema from congestive heart failure. The results indicate that in such patients, the diuresis produced has the relationship of a simple osmotic diuresis. The clinical implications are discussed.

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