Open AccessSevere Acidosis and Hyperpotassemia Treated with Sodium Bicarbonate Infusion
Author(s) -
KUNO C. SCHWARZ,
Burton D. Cohen,
Glenn D. Lubash,
Albert L. Rubin
Publication year - 1959
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.19.2.215
Subject(s) - medicine , sodium bicarbonate , acidosis , bicarbonate , metabolic acidosis , anesthesia , sodium , potassium , toxicity , organic chemistry , chemistry
Four uremic patients with severe acidosis, hyperpotassemia, and electrocardiographic signs of toxicity were treated with intravenous sodium bicarbonate. Serial determinations showed a fall in plasma potassium, a rise in blood pH, and regression of the electrocardiogram toward normal. The mechanisms responsible for these changes are discussed.
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