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The Pathology of Hypertensive Pulmonary Vascular Disease
Author(s) -
Donald Heath,
Jesse E. Edwards
Publication year - 1958
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.18.4.533
Subject(s) - medicine , pulmonary arterial pressure , pulmonary hypertension , complication , pathology , cardiology , pulmonary vasculature , blood pressure , vascular disease
Progressive histologic changes occur in the pulmonary arteries and arterioles, as a complication of chronically elevated pulmonary arterial blood pressure, in patients with congenital septal defects of the heart. This progression is so stereotyped as to allow a division of the structural effects into 6 grades. The histologic features of each grade are described in detail in this communication. These results afford a basis for comparing the magnitude of these changes to the clinical findings.

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