Sodium Chloride Excretion Following Salt Loading in Hypertensive Subjects | Zendy

P Cottier | Zendy; John M. Weller | Zendy; Sibley W. Hoobler | Zendy

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Sodium Chloride Excretion Following Salt Loading in Hypertensive Subjects

Author(s) -

P Cottier,

John M. Weller,

Sibley W. Hoobler

Publication year - 1958

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.18.2.196

Subject(s) - sodium , medicine , excretory system , chloride , electrolyte , endocrinology , excretion , abnormality , kidney , metallurgy , chemistry , materials science , electrode , psychiatry

Patients with essential hypertension show an altered renal excretory response to sodium chloride loading. Hypertensive patients acutely eliminate a greater proportion of a salt and water load than do normotensive subjects. This renal abnormality appears to be due to an augmented tubular rejection of sodium chloride and water. This study further defines the nature and extent of this alteration in electrolyte and water metabolism.

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