Open AccessAssociation of Aortic Valvular Disease and Cystic Medial Necrosis of the Ascending Aorta
Author(s) -
Victor A. McKusick,
R.Bruce Logue,
Henry T. Bahnson
Publication year - 1957
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.16.2.188
Subject(s) - medicine , ascending aorta , regurgitation (circulation) , stenosis , cardiology , aorta , hemodynamics , aortic valve , aneurysm , valvular heart disease , aortic aneurysm , radiology
In 4 patients with aortic stenosis and regurgitation, progressive dilatation of the ascending aorta and dissecting aneurysm developed. Cystic medial necrosis was discovered histologically. It is suggested that the change in the aorta is secondary to hemodynamic stresses imposed by the disease at the aortic valve.
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