Pressor Effects of Norepinephrine After Drastic Reduction of Sodium Intake
Author(s) -
Lewis K. Dahl
Publication year - 1957
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.15.2.231
Subject(s) - norepinephrine , medicine , blood pressure , sodium , pressor response , endocrinology , high sodium , anesthesia , heart rate , dopamine , chemistry , organic chemistry
The mechanisms whereby dietary sodium restriction leads to decreased arterial blood pressure is obscure. Previously reported studies of patients with arterial hypertension showed a lessened pressor response to norepinephrine after sodium restriction. In the present investigations, reduction in pressor response to norepinephrine during the low sodium period was observed only occasionally; sodium restriction decreases blood pressure in some hypertensive patients by other unknown mechanisms.
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