Hemolytic Syndrome Following the Insertion of a Lucite Ball Valve Prosthesis into the Cardiovascular System
Author(s) -
Frederick Stohlman,
Stanley J. Sarnoff,
Robert B. Case,
A. T. Ness
Publication year - 1956
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.13.4.586
Subject(s) - medicine , reticulocytosis , aortic valve , ball valve , cardiology , surgery , mitral valve , prosthesis , anemia , structural engineering , engineering
Permanent bypass of the aortic valve was accomplished in the dog by placing a lucite conduit containing a Hufnagel valve between the left ventricular apex and thoracic aorta. Red cell destruction was produced by the valve in this position and was accompanied by hemoglobinemia, hemoglobinuria, anemia, reticulocytosis and renal hemosiderosis. Red cell survival, as determined with Cr51, was markedly shortened.
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