Open AccessInfluence of Prostigmine and Acetylcholine on Ventricular Fibrillation Elicited by Focal Cooling
Author(s) -
David Scherf,
R. Bussan,
William C. Gittinger,
S. Torin
Publication year - 1955
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.12.4.620
Subject(s) - ventricle , medicine , acetylcholine , ventricular fibrillation , fibrillation , cardiology , atrial fibrillation , anesthesia
Focal cooling of the exposed ventricle of the dog, beating at high rates, elicits ventricular fibrillation within a few seconds. The effect of this mode of cooling on hearts pre-treated with prostigmine or acetylcholine is studied. These compounds do not prevent ventricular fibrillation, but on the contrary some observations show that they enhance its appearance.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom