Insulin Resistance, Hyperlipidemia, and Hypertension in Mice Lacking Endothelial Nitric Oxide Synthase | Zendy

Hervé Duplain | Zendy; Rémy Burcelin | Zendy; Cláudio Sartori | Zendy; Stéphane Cook | Zendy; Marc Egli | Zendy; Mattia Lepori | Zendy; Péter Vollenweider | Zendy; Thierry Pedrazzini | Zendy; Pascal Nicod | Zendy; Bernard Thorens | Zendy; Urs Scherrer | Zendy

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Insulin Resistance, Hyperlipidemia, and Hypertension in Mice Lacking Endothelial Nitric Oxide Synthase

Author(s) -

Hervé Duplain,

Rémy Burcelin,

Cláudio Sartori,

Stéphane Cook,

Marc Egli,

Mattia Lepori,

Péter Vollenweider,

Thierry Pedrazzini,

Pascal Nicod,

Bernard Thorens,

Urs Scherrer

Publication year - 2001

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.104.3.342

Subject(s) - medicine , hyperlipidemia , insulin resistance , nitric oxide synthase , nitric oxide , endothelial nitric oxide synthase , endocrinology , insulin , diabetes mellitus , enos

Insulin resistance and arterial hypertension are related, but the underlying mechanism is unknown. Endothelial nitric oxide synthase (eNOS) is expressed in skeletal muscle, where it may govern metabolic processes, and in the vascular endothelium, where it regulates arterial pressure.

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