Does Amlodipine Increase Cancer Incidence?
Author(s) -
Larry B. Goldstein
Publication year - 2001
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.104.2.e5
Subject(s) - amlodipine , medicine , randomized controlled trial , incidence (geometry) , cancer , placebo , cardiology , blood pressure , physics , alternative medicine , pathology , optics
To the Editor:The Prospective Randomized Evaluation of the Vascular Effects of Norvasc Trial (PREVENT)1 amplifies the controversy over calcium antagonists and increased cancer risk.2 In this 36-month, placebo-controlled, randomized trial, the calcium antagonist amlodipine had no effect on the angiographic progression of coronary atherosclerosis or on the risk of major cardiovascular events. In the group assigned to amlodipine, the annualized rates of coronary …
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