Open AccessAntithrombotic Effects of Flavonoid
Author(s) -
Shinya Goto,
Shunnosuke Handa
Publication year - 2001
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.103.4.e23
Subject(s) - medicine , flavonoid , antithrombotic , von willebrand factor , abciximab , pharmacology , platelet membrane glycoprotein , thrombus , platelet , cardiology , biochemistry , percutaneous coronary intervention , antioxidant , chemistry , myocardial infarction
To the Editor: We read with interest the article by Mruk and colleagues1 demonstrating the antithrombotic and antispastic effects of flavone-8-acetic acid (flavonoid) in an animal model of a deep arterial injury. The authors conclude that “Flavonoid markedly reduced platelet deposition, mural thrombi, and injury-induced vasoconstriction after deep arterial injury, suggesting that a major inhibition of platelet glycoprotein Ibα may be beneficial therapy.”In our opinion, a major …
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