Open AccessPlasminogen Activator Inhibitor-1 and Its Cofactor Vitronectin Stabilize Arterial Thrombi After Vascular Injury in Mice
Author(s) -
Stavros Konstantinides,
Katrin Schäfer,
T Thinnes,
David J. Loskutoff
Publication year - 2001
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.103.4.576
Subject(s) - medicine , thrombus , vitronectin , plasminogen activator inhibitor 1 , thrombolysis , thrombosis , plasminogen activator , tissue plasminogen activator , endocrinology , pathology , receptor , myocardial infarction , integrin
The origin and contribution of plasminogen activator inhibitor-1 (PAI-1) and its cofactor vitronectin (VN) to arterial thrombosis/thrombolysis in vivo is controversial.
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