Open AccessAngiotensin II–Induced Hypertension Accelerates the Development of Atherosclerosis in ApoE-Deficient Mice
Author(s) -
Daiana Weiss,
John J. Kools,
W. Robert Taylor
Publication year - 2001
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.103.3.448
Subject(s) - angiotensin ii , medicine , endocrinology , lesion , apolipoprotein e , renin–angiotensin system , angiotensin iii , angiotensin ii receptor type 1 , blood pressure , pathology , disease
Angiotensin II may contribute to the development and progression of atherosclerotic lesions because of its growth and proinflammatory effects. We sought to determine whether angiotensin II-induced hypertension would augment and accelerate the development of atherosclerotic lesions in apoE-deficient mice.
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