Morphine Mimics Preconditioning via Free Radical Signals and Mitochondrial K ATP Channels in Myocytes
Author(s) -
Bradley C. McPherson,
Zhenhai Yao
Publication year - 2001
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.103.2.290
Subject(s) - morphine , medicine , pharmacology , antagonist , agonist , opioid receptor , cardioprotection , opioid , endocrinology , receptor , ischemia
We tried to determine whether morphine mimics preconditioning (PC) to reduce cell death in cultured cardiomyocytes and whether opioid delta(1) receptors, free radicals, and K(ATP) channels mediate this effect.
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