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Enoxaparin inhibits smooth muscle cell proliferation in experimental models. Intimal hyperplasia has been found to be the principal cause of restenosis after coronary stent implantation. We sought to determine whether the intramural delivery of enoxaparin before stenting of de novo lesions decreases restenosis.

Local Delivery of Enoxaparin to Decrease Restenosis After Stenting: Results of Initial Multicenter Trial