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Local Delivery of Enoxaparin to Decrease Restenosis After Stenting: Results of Initial Multicenter Trial
Author(s) -
R. Stefan Kiesz,
Paweł Buszman,
Jack L. Martin,
Ezra Deutsch,
M. M. Rozek,
Ewa Gaszewska,
Marek Rewicki,
Piotr Seweryniak,
Maciej Kośmider,
Michał Tendera
Publication year - 2001
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.103.1.26
Subject(s) - medicine , restenosis , multicenter study , cardiology , coronary stenting , stent , randomized controlled trial
Enoxaparin inhibits smooth muscle cell proliferation in experimental models. Intimal hyperplasia has been found to be the principal cause of restenosis after coronary stent implantation. We sought to determine whether the intramural delivery of enoxaparin before stenting of de novo lesions decreases restenosis.

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