Open AccessVEGF Gene Delivery to Myocardium
Author(s) -
Randall J. Lee,
Matthew L. Springer,
William Blanco-Bose,
Robin Shaw,
Philip C. Ursell,
Helen M. Blau
Publication year - 2000
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.102.8.898
Subject(s) - cd31 , medicine , angiogenesis , vascular endothelial growth factor , gene delivery , immunohistochemistry , pathology , myocyte , genetic enhancement , vascular endothelial growth factor a , endothelium , cancer research , endocrinology , biology , gene , vegf receptors , biochemistry
Vascular endothelial growth factor (VEGF) is being investigated for therapeutic angiogenesis in ischemic myocardium. Primarily, transient delivery systems have been tested. The goal of this study was to investigate the effects of continuous expression of VEGF in myocardium by use of myoblast-mediated delivery.
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