Open AccessHerpesvirus Infection Accelerates Atherosclerosis in the Apolipoprotein E–Deficient Mouse
Author(s) -
Dagmar G. Alber,
Kenneth L. Powell,
Patrick Vallance,
David A. Goodwin,
Cairistine GrahameClarke
Publication year - 2000
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.102.7.779
Subject(s) - apolipoprotein e , medicine , atheroma , immunology , lesion , pathogenesis , virus , virology , pathology , disease
Human herpesviruses have been implicated but not proven to be involved in the etiology of atherosclerosis. To determine whether there is a causal relationship, the effect of herpesvirus infection on the development of atherosclerosis was assessed in the apolipoprotein E-deficient (apoE-/-) mouse.
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