Open AccessDifferential Effects of Oral and Transdermal Estrogen Replacement Therapy on Endothelial Function in Postmenopausal Women
Author(s) -
Satu Vehkavaara,
Tiina HakalaAlaPietilä,
Antti Virkamäki,
Robert Bergholm,
Christian Ehnholm,
Outi Hovatta,
MarjaRiitta Taskinen,
Hannele YkiJärvinen
Publication year - 2000
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.102.22.2687
Subject(s) - medicine , transdermal , placebo , endothelium , estrogen , endocrinology , sodium nitroprusside , vasodilation , oral administration , acetylcholine , pharmacology , nitric oxide , alternative medicine , pathology
We determined whether the vascular effects of estradiol depend on the route of administration by comparing the effects of oral estradiol and transdermal placebo, transdermal estradiol and oral placebo, and transdermal placebo and oral placebo on in vivo endothelial function in 27 postmenopausal women.
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