Open AccessWidening of the Excitable Gap During Pharmacological Cardioversion of Atrial Fibrillation in the Goat
Author(s) -
M. C. E. F. Wijffels,
Rick Dorland,
F. Mast,
Maurits A. Allessie
Publication year - 2000
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.102.2.260
Subject(s) - flecainide , sotalol , medicine , cardiology , cardioversion , atrial fibrillation , refractory period , dofetilide , anesthesia
Previous studies suggest that the antifibrillatory action of class I and III drugs is due to prolongation of the atrial wavelength. The aim of the present study was to directly evaluate the electrophysiological action of antifibrillatory drugs in a goat model of chronic atrial fibrillation (AF).
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