Insertion/Deletion Polymorphism of the Angiotensin I-Converting Enzyme Gene Is Not Associated With Restenosis After Coronary Stent Placement | Zendy

Werner Koch | Zendy; Adnan Kastrati | Zendy; Julinda Mehilli | Zendy; Corinna Böttiger | Zendy; Nicolas von Beckerath | Zendy; Albert Schömig | Zendy

Open Access

Insertion/Deletion Polymorphism of the Angiotensin I-Converting Enzyme Gene Is Not Associated With Restenosis After Coronary Stent Placement

Author(s) -

Werner Koch,

Adnan Kastrati,

Julinda Mehilli,

Corinna Böttiger,

Nicolas von Beckerath,

Albert Schömig

Publication year - 2000

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.102.2.197

Subject(s) - medicine , restenosis , cardiology , genotype , myocardial infarction , clinical endpoint , coronary artery disease , stent , angiotensin converting enzyme , gene , clinical trial , blood pressure , biochemistry , chemistry

The renin-angiotensin system is thought to play a role in coronary thrombosis and restenosis. Plasma angiotensin I-converting enzyme (ACE) activity is associated with an insertion/deletion polymorphism in the gene coding for ACE. The objective of this study was to test the hypothesis that the D allele of the ACE gene is associated with a higher risk for restenosis after coronary stent placement.

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