Vascular Endothelial Growth Factor-A–Induced Chemotaxis of Monocytes Is Attenuated in Patients With Diabetes Mellitus
Author(s) -
Johannes Waltenberger,
Juliane Lange,
Andrea Kranz
Publication year - 2000
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.102.2.185
Subject(s) - medicine , monocyte , chemotaxis , vascular endothelial growth factor , endocrinology , ex vivo , diabetes mellitus , in vivo , immunology , receptor , vegf receptors , biology , microbiology and biotechnology
Vascular endothelial growth factor-A (VEGF-A) acts on endothelial cells and monocytes, 2 cell types that participate in the angiogenic and arteriogenic process in vivo. Thus far, it has not been possible to identify differences in individual responses to VEGF-A stimulation because of the lack of an ex vivo assay.
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