High-Efficiency, Long-Term Cardiac Expression of Foreign Genes in Living Mouse Embryos and Neonates | Zendy

Geir Christensen | Zendy; Susumu Minamisawa | Zendy; Peter J. Gruber | Zendy; Yibin Wang | Zendy; Kenneth R. Chien | Zendy

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High-Efficiency, Long-Term Cardiac Expression of Foreign Genes in Living Mouse Embryos and Neonates

Author(s) -

Geir Christensen,

Susumu Minamisawa,

Peter J. Gruber,

Yibin Wang,

Kenneth R. Chien

Publication year - 2000

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.101.2.178

Subject(s) - cre recombinase , transgene , gene expression , embryonic stem cell , biology , intracardiac injection , genetically modified mouse , viral vector , microbiology and biotechnology , embryo , genetic enhancement , gene , myocyte , context (archaeology) , somatic cell , medicine , genetics , recombinant dna , paleontology

The development of improved strategies for efficient and reproducible in vivo gene transfer into the murine heart will ultimately allow the intersection of somatic and germline gene transfer strategies to study complex features of cardiac biology and diseases.

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