Open AccessVentricular Pacing With Premature Excitation for Treatment of Hypertensive-Cardiac Hypertrophy With Cavity-Obliteration
Author(s) -
David A. Kass,
Chen-Huan Chen,
Maurice Talbot,
Carlos Eduardo Rochitte,
João A.C. Lima,
Ronald D. Berger,
Hugh Calkins
Publication year - 1999
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.100.8.807
Subject(s) - medicine , cardiology , dobutamine , stroke volume , cardiac output , crossover study , ejection fraction , anesthesia , hemodynamics , heart failure , pathology , placebo , alternative medicine
Hypertensive left ventricular hypertrophy with supranormal systolic ejection and distal cavity obliteration (HHCO) can result in debilitating exertional fatigue and dyspnea. Dual-chamber pacing with ventricular preactivation generates discoordinate contraction, which can limit cavity obliteration and thereby increase potential ejection reserve. Accordingly, we hypothesized that pacing may improve exercise tolerance long-term in this syndrome.
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