Effect of Postmenopausal Hormones on Inflammation-Sensitive Proteins | Zendy

Mary Cushman | Zendy; Claudine Legault | Zendy; Elizabeth BarrettConnor | Zendy; Marcia L. Stefanick | Zendy; Craig M. Kessler | Zendy; Howard L. Judd | Zendy; Pamela A. Sakkinen | Zendy; Russell P. Tracy | Zendy

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Effect of Postmenopausal Hormones on Inflammation-Sensitive Proteins

Author(s) -

Mary Cushman,

Claudine Legault,

Elizabeth BarrettConnor,

Marcia L. Stefanick,

Craig M. Kessler,

Howard L. Judd,

Pamela A. Sakkinen,

Russell P. Tracy

Publication year - 1999

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.100.7.717

Subject(s) - medicine , c reactive protein , placebo , von willebrand factor , hormone , estrogen , inflammation , progestin , hormone therapy , endocrinology , risk factor , gastroenterology , breast cancer , pathology , cancer , platelet , alternative medicine

Observational studies in healthy women suggest postmenopausal hormone therapy reduces risk of coronary events. In contrast, in a recent clinical trial of women with coronary disease, a subgroup analysis demonstrated increased risk during the early months of therapy. Because higher levels of inflammation factors predict vascular disease outcomes, the effect of hormones on these factors is of interest.

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