Enhanced Sympathetic and Ventilatory Responses to Central Chemoreflex Activation in Heart Failure | Zendy

Krzysztof Narkiewicz | Zendy; Catherine A. Pesek | Zendy; Philippe J. H. van de Borne | Zendy; Masahiko Kato | Zendy; Virend K. Somers | Zendy

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Enhanced Sympathetic and Ventilatory Responses to Central Chemoreflex Activation in Heart Failure

Author(s) -

Krzysztof Narkiewicz,

Catherine A. Pesek,

Philippe J. H. van de Borne,

Masahiko Kato,

Virend K. Somers

Publication year - 1999

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.100.3.262

Subject(s) - medicine , hypercapnia , heart failure , heart rate , cardiology , ventilation (architecture) , blood pressure , anesthesia , hypoxia (environmental) , sympathetic nervous system , cold pressor test , respiratory system , mechanical engineering , chemistry , organic chemistry , oxygen , engineering

Sympathetic activation and respiratory abnormalities may each be implicated in the pathophysiology of congestive heart failure (CHF). Chemoreflexes are an important mechanism regulating both sympathetic drive and breathing. We therefore tested the hypothesis that chemoreflex function is altered in CHF.

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