Effects of Growth Hormone Supplementation on Left Ventricular Morphology and Myocyte Function With the Development of Congestive Heart Failure | Zendy

Ward V. Houck | Zendy; Lydia C. Pan | Zendy; Scott B. Kribbs | Zendy; Mark J. Clair | Zendy; George McDaniel | Zendy; R. Stephen Krombach | Zendy; William M. Merritt | Zendy; C.M. Pirie | Zendy; Julie P. Iannini | Zendy; Rupak Mukherjee | Zendy; Francis G. Spinale | Zendy

Open Access

Effects of Growth Hormone Supplementation on Left Ventricular Morphology and Myocyte Function With the Development of Congestive Heart Failure

Author(s) -

Ward V. Houck,

Lydia C. Pan,

Scott B. Kribbs,

Mark J. Clair,

George McDaniel,

R. Stephen Krombach,

William M. Merritt,

C.M. Pirie,

Julie P. Iannini,

Rupak Mukherjee,

Francis G. Spinale

Publication year - 1999

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.100.19.2003

Subject(s) - medicine , heart failure , cardiology , endocrinology , myocyte , cardiac function curve , heart disease , fractional shortening , hormone

Release of growth hormone (GH), putatively through alterations in insulin growth factor-1 (IGF-1) levels, has been implicated to influence left ventricular (LV) myocardial structure and function. The objective of this study was to determine contributory mechanisms by which GH supplementation may influence LV function with the development of congestive heart failure (CHF).

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