Measurement of Atropine-Induced Vascular Pooling | Zendy

Robert D. Miller | Zendy; Martin H. Kalser | Zendy; Charles Frye | Zendy; Archer S. Gordon | Zendy

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Measurement of Atropine-Induced Vascular Pooling

Author(s) -

Robert D. Miller,

Martin H. Kalser,

Charles Frye,

Archer S. Gordon

Publication year - 1954

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.10.3.423

Subject(s) - medicine , atropine , abdomen , anesthesia , peripheral , pooling , compression (physics) , cardiology , surgery , materials science , artificial intelligence , computer science , composite material

Postural hypotension resulting from 2 mg. of intramuscular atropine appears to be due to peripheral vascular pooling. Controlled studies on 31 normal adult males are reported here and reveal that external compression of the abdomen and lower extremities allows partial cardiovascular compensation. Simultaneous compression of both legs and abdomen is even more effective in preventing postural hypotension. The effects of 2 mg. of atropine appear to be due to partial vagal block, partial ganglionic block and central excitation.

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