Postural Hypotension Induced by Atropine Sulfate | Zendy

Martin H. Kalser | Zendy; Charles Frye | Zendy; Archer S. Gordon | Zendy

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Postural Hypotension Induced by Atropine Sulfate

Author(s) -

Martin H. Kalser,

Charles Frye,

Archer S. Gordon

Publication year - 1954

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.10.3.413

Subject(s) - atropine , medicine , placebo , anesthesia , blood pressure , atropine sulfate , alternative medicine , pathology

Previous tests on the use of large doses of atropine for the treatment of anticholinesterase poisoning have revealed postural hypotension following the administration of 2 mg. of this drug. In this study on 78 normal adult males, the cardiovascular responses to positional change after 2 mg. atropine have been measured and the mechanisms elucidated. Blood pressure response to tilting was normal during control and placebo phases, but showed a profound alteration after atropine.

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