The Clinical Effect of Dihydroergocornine Methanesulphonate (DHO-180) in Arterial Hypertension: A Preliminary Report | Zendy

Ralph M. Tandowsky | Zendy

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The Clinical Effect of Dihydroergocornine Methanesulphonate (DHO-180) in Arterial Hypertension: A Preliminary Report

Author(s) -

Ralph M. Tandowsky

Publication year - 1950

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/01.cir.1.4.686

Subject(s) - medicine , blood pressure , cardiology , diastole , drug , pulse pressure , antihypertensive drug , pharmacology

A controlled clinical and statistical study of 47 unselected patients with sustained arterial hypertension who received dihydroergocornine intravenously and orally is presented. The study demonstrates the central effect of this drug in temporarily lowering the systolic and diastolic blood pressure and pulse rate. This action occurs irrespective of associated pathology or extent of the hypertensive state when the drug is given parenterally. Orally, little effect was demonstrated.

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