Open AccessDeterminants of Elevated Pulse Pressure in Middle-Aged and Older Subjects With Uncomplicated Systolic Hypertension
Author(s) -
Gary F. Mitchell,
Yves Lacourcière,
Jean-Pascal Ouellet,
Joseph L. Izzo,
Joel Neutel,
Linda Kerwin,
A. Jay Block,
Marc A. Pfeffer
Publication year - 2003
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.0000093435.04334.1f
Subject(s) - medicine , pulse pressure , cardiology , pulse wave velocity , arterial stiffness , blood pressure , aorta , systole , pulsatile flow , hemodynamics , diastole
Elevated pulse pressure (PP) is associated with increased cardiovascular risk and is thought to be secondary to elastin fragmentation with secondary collagen deposition and stiffening of the aortic wall, leading to a dilated, noncompliant vasculature.
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