Open AccessContrasting Effects of Oral Versus Transdermal Estrogen on Serum Amyloid A (SAA) and High-Density Lipoprotein–SAA in Postmenopausal Women
Author(s) -
Aamer Abbas,
Paul J. Fadel,
Zhongyun Wang,
Debbie Arbique,
Ishwarlal Jialal,
Wanpen Vongpatanasin
Publication year - 2004
Publication title -
arteriosclerosis, thrombosis, and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/01.atv.0000140198.16664.8e
Subject(s) - serum amyloid a , medicine , estrogen , endocrinology , transdermal , serum amyloid a protein , lipoprotein , apolipoprotein b , cholesterol , pharmacology , inflammation
Previous studies indicated that oral estrogen increased C-reactive protein by a first-pass hepatic effect. In this study, we determine whether the route of estrogen administration influences serum amyloid A (SAA), another acute-phase protein produced by the liver, and the SAA content of the high-density lipoprotein (HDL-SAA) in postmenopausal women.