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To investigate in a randomized, double-blinded, placebo controlled, crossover study the effect of a single dose of the nonselective β-adrenergic receptor antagonist propranolol (40 mg) on hypertonic saline (HS)-evoked masseter muscle pain and autonomic activity during rest and during a mental arithmetic task (Paced Auditory Serial Addition Task, PASAT).

Effect of Propranolol on Hypertonic Saline-Evoked Masseter Muscle Pain and Autonomic Response in Healthy Women During Rest and Mental Arithmetic Task