Impact of Extended Duration of Polymyxin B-Immobilized Fiber Column Direct Hemoperfusion on Hemodynamics, Vasoactive Substance Requirement, and Pulmonary Oxygenation in Patients with Sepsis: An Observational Study | Zendy

Chieko Mitaka | Zendy; Makio Kusao | Zendy; Izumi Kawagoe | Zendy; Daizoh Satoh | Zendy; Toshiaki Iba | Zendy; Claudio Ronco | Zendy

Open Access

Impact of Extended Duration of Polymyxin B-Immobilized Fiber Column Direct Hemoperfusion on Hemodynamics, Vasoactive Substance Requirement, and Pulmonary Oxygenation in Patients with Sepsis: An Observational Study

Author(s) -

Chieko Mitaka,

Makio Kusao,

Izumi Kawagoe,

Daizoh Satoh,

Toshiaki Iba,

Claudio Ronco

Publication year - 2021

Publication title -

blood purification

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.686

H-Index - 57

eISSN - 1421-9735

pISSN - 0253-5068

DOI - 10.1159/000515685

Subject(s) - hemoperfusion , sofa score , medicine , septic shock , renal replacement therapy , sepsis , mean arterial pressure , inotrope , anesthesia , hemodynamics , apache ii , cardiology , hemodialysis , blood pressure , heart rate , intensive care unit

Polymyxin B-immobilized fiber column direct hemoperfusion (PMX-DHP) is used for patients with septic shock, and the recommended hemoperfusion period is 2 h. However, it remains unclear whether the optimal duration is 2 h or longer. The purpose of this study was to compare the effects of PMX-DHP between conventional and longer duration of PMX-DHP.

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