Non-inflammatory posterior uveitis – Diagnosis and therapy

Background: Posterior uveitis is a rare, potentially serious condition. In Central Europe and the USA, the incidence of intraocular inflammation is approximately 115/100,000 and of these cases, 12–15% suffer from posterior uveitis. This disease occurs more frequently in adults than in children. The disease description of “posterior uveitis” includes manifestations such as choroiditis, retinitis, chorioretinitis, retinochoroiditis and neuroretinitis. The primary site of inflammation is predominantly in the choroid or retina. The clinical picture can have a very heterogeneous presentation which is primarily due to the multifactorial aetiology: The disease can be due to infectious as well as non-infectious causes and can occur with or without associated systemic disease. In rare cases, it is also possible for a masquerade syndrome (benign or malignant) to simulate posterior uveitis.