Tumor-Infiltrating Lymphocytes in Biopsy Specimens Obtained 7 Days after Starting Chemoradiotherapy for Rectal Cancer Are Predictors of the Response to Chemoradiotherapy | Zendy

Hiroshi Miyakita | Zendy; Sotaro Sadahiro | Zendy; Toshiyuki Suzuki | Zendy; Lin Fung Chan | Zendy; Takashi Ogimi | Zendy; Kazutake Okada | Zendy; Seiichiro Yamamoto | Zendy; Hiroshi Kajiwara | Zendy

Open Access

Tumor-Infiltrating Lymphocytes in Biopsy Specimens Obtained 7 Days after Starting Chemoradiotherapy for Rectal Cancer Are Predictors of the Response to Chemoradiotherapy

Author(s) -

Hiroshi Miyakita,

Sotaro Sadahiro,

Toshiyuki Suzuki,

Lin Fung Chan,

Takashi Ogimi,

Kazutake Okada,

Seiichiro Yamamoto,

Hiroshi Kajiwara

Publication year - 2020

Publication title -

oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.987

H-Index - 98

eISSN - 1423-0232

pISSN - 0030-2414

DOI - 10.1159/000508922

Subject(s) - tumor infiltrating lymphocytes , medicine , biopsy , colorectal cancer , cd8 , h&e stain , foxp3 , staining , pathology , lymphocyte , gastroenterology , cancer , immune system , immunology

Neoadjuvant chemoradiotherapy (nCRT) followed by total mesorectal excision surgery is a standard treatment for locally advanced rectal cancer (LARC). Tumor-infiltrating lymphocytes (TILs) have been reported to be associated with tumor response; however, this remains to be established. We previously reported that histological changes on biopsy specimens obtained 7 days after starting nCRT are strong predictors of response to nCRT.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research